{"id":5645,"date":"2022-11-03T08:45:34","date_gmt":"2022-11-03T08:45:34","guid":{"rendered":"https:\/\/www.vygon.de\/unternehmen\/?post_type=landingpages&p=5645"},"modified":"2025-03-17T11:23:31","modified_gmt":"2025-03-17T10:23:31","slug":"neonatologie-beatmung","status":"publish","type":"landingpages","link":"https:\/\/www.vygon.de\/unternehmen\/lp\/neonatologie-beatmung\/","title":{"rendered":"Beatmung – LISA Methode"},"content":{"rendered":"

[et_pb_section fb_built=“1″ admin_label=“Hero“ _builder_version=“4.20.4″ background_color=“#084666″ use_background_color_gradient=“on“ background_color_gradient_direction=“170deg“ background_color_gradient_stops=“rgba(0,46,79,0.13) 1%|rgba(8,70,102,0.8) 100%“ background_color_gradient_overlays_image=“on“ background_color_gradient_start=“rgba(0,46,79,0.13)“ background_color_gradient_start_position=“1%“ background_color_gradient_end=“rgba(8,70,102,0.8)“ background_image=“https:\/\/www.vygon.de\/unternehmen\/wp-content\/uploads\/2022\/06\/Neonatologie-Enterale-Ernaehrung-height.jpg“ background_size=“initial“ background_position=“top_center“ min_height=“636px“ custom_padding=“100px||||false|false“ bottom_divider_height=“181px“ bottom_divider_flip=“horizontal“ bottom_divider_style_tablet=““ bottom_divider_style_phone=““ bottom_divider_style_last_edited=“on|phone“ hover_transition_speed_curve=“ease-in“ global_colors_info=“{}“][et_pb_row use_custom_gutter=“on“ gutter_width=“1″ _builder_version=“4.20.4″ background_size=“initial“ background_position=“top_left“ background_repeat=“repeat“ custom_margin=“||80px||false|false“ custom_padding=“27px|0px|27px|0px|false|false“ global_colors_info=“{}“][et_pb_column type=“4_4″ _builder_version=“4.16″ custom_padding=“|||“ global_colors_info=“{}“ custom_padding__hover=“|||“][et_pb_text _builder_version=“4.17.0″ text_font=“||||||||“ text_font_size=“20px“ header_font=“Open Sans|800|||||||“ header_font_size=“60px“ header_line_height=“1.3em“ background_size=“initial“ background_position=“top_left“ background_repeat=“repeat“ background_layout=“dark“ max_width=“1054px“ custom_margin=“|||“ custom_margin_tablet=“|100px||“ custom_margin_phone=“|30px||“ custom_margin_last_edited=“off|desktop“ custom_padding=“|||0px||“ header_font_size_tablet=“50px“ header_font_size_phone=“40px“ header_font_size_last_edited=“on|phone“ header_line_height_tablet=““ header_line_height_phone=““ header_line_height_last_edited=“on|desktop“ global_colors_info=“{}“]<\/p>\n

Atemnotsyndrom des Fr\u00fchgeborenen<\/h1>\n

Das Krankheitsbild des Atemnotsyndroms ist f\u00fcr einen gro\u00dfen Anteil der neonatalen Morbidit\u00e4t und Mortalit\u00e4t verantwortlich.1<\/a><\/sup><\/span><\/p>\n

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RISIKEN<\/h3>\n

Das Atemnotsyndrom (ANS) des Fr\u00fchgeborenen ist eine akut lebensbedrohliche, pulmonale Erkrankung, die auf einer unreifen Lunge und Surfactant-Mangel beruht.2<\/a><\/sup><\/span><\/p>\n

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3<\/span><\/p>\n

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Folgen<\/h3>\n

Bei der Behandlung des Atemnotsyndroms durch eine maschinelle Beatmung, besteht ein hohes Risiko einer Dysplasie (kurz BPD, chronische Lungenerkrankung des Fr\u00fchgeborenen).<\/a>3<\/a><\/sup><\/span><\/p>\n

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3<\/span><\/p>\n

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L\u00f6sungen<\/h3>\n

Zahlreiche Studien belegen, dass durch die non-invasive Surfactant-Applikation (LISA-Methode) es zu einer Vermeidung von Komplikationen der maschinellen Beatmung kommen kann.4<\/a><\/sup><\/span><\/p>\n

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3<\/span><\/p>\n

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Risiken<\/p>\n

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Das Atemnotsyndrom des Fr\u00fchgeborenen, kurz ANS, ist eine akut lebensbedrohliche pulmonale Erkrankung, die auf einer unreifen Lunge und Surfactant-Mangel beruht. Das Krankheitsbild ist f\u00fcr einen gro\u00dfen Anteil der neonatalen Morbidit\u00e4t und Mortalit\u00e4t verantwortlich.<\/p>\n

Etwa 60 bis 80 % der Fr\u00fchgeborenen (< 28 SSW) entwickeln ein Atemnotsyndrom. Es handelt sich dabei um die h\u00e4ufigste Todesursache in der Neonatalzeit.5<\/a><\/sup><\/span><\/p>\n

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Folgen<\/p>\n

[\/et_pb_text][et_pb_divider color=“gcid-d08e7a08-b747-4a4e-bec9-6f46a3c29f19″ divider_weight=“4px“ _builder_version=“4.17.0″ _module_preset=“default“ width=“15%“ custom_margin=“0px||0px||false|false“ custom_padding=“0px||0px||false|false“ global_colors_info=“{%22gcid-d08e7a08-b747-4a4e-bec9-6f46a3c29f19%22:%91%22color%22%93}“][\/et_pb_divider][et_pb_text _builder_version=“4.17.0″ _module_preset=“default“ header_3_font=“Open Sans||||||||“ header_3_text_color=“gcid-f7280f3d-17cc-4d2a-9e34-a7b8316cf68e“ header_3_font_size=“25px“ header_3_line_height=“1.3em“ header_3_font_tablet=““ header_3_font_phone=““ header_3_font_last_edited=“on|phone“ global_colors_info=“{%22gcid-f7280f3d-17cc-4d2a-9e34-a7b8316cf68e%22:%91%22header_3_text_color%22,%22header_3_text_color%22%93}“]<\/p>\n

Neben den physiologischen Entstehungsfaktoren beg\u00fcnstigt eine invasive Beatmungsform das Aufkommen eines ANS. Die maschinelle Beatmung hat vor allem bei Fr\u00fchgeborenen ein sehr hohes Sch\u00e4digungspotenzial. Die bronchopulmonale Dysplasie (kurz BPD, chronische Lungenerkrankung des Fr\u00fchgeborenen) wird vor allem durch maschinelle Beatmung verursacht.6<\/a><\/sup><\/span><\/p>\n

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der Fr\u00fchgeborenen mit einem Geburtsgewicht < 1.000 g oder einer Schwangerschaftsdauer von < 28 Wochen erkranken an einer BPD.7<\/a><\/sup><\/span><\/p>\n

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L\u00f6sungen<\/p>\n

[\/et_pb_text][et_pb_divider color=“gcid-d08e7a08-b747-4a4e-bec9-6f46a3c29f19″ divider_weight=“4px“ _builder_version=“4.17.0″ _module_preset=“default“ width=“15%“ custom_margin=“0px||0px||false|false“ custom_padding=“0px||0px||false|false“ global_colors_info=“{%22gcid-d08e7a08-b747-4a4e-bec9-6f46a3c29f19%22:%91%22color%22%93}“][\/et_pb_divider][et_pb_text _builder_version=“4.17.0″ _module_preset=“default“ header_3_font=“Open Sans||||||||“ header_3_text_color=“gcid-f7280f3d-17cc-4d2a-9e34-a7b8316cf68e“ header_3_font_size=“25px“ header_3_line_height=“1.3em“ header_3_font_tablet=““ header_3_font_phone=““ header_3_font_last_edited=“on|phone“ global_colors_info=“{%22gcid-f7280f3d-17cc-4d2a-9e34-a7b8316cf68e%22:%91%22header_3_text_color%22,%22header_3_text_color%22%93}“]<\/p>\n

Die non-invasive Surfactant-Applikation (LISA<\/strong>-Methode) ist eine Kombination aus nasaler CPAP-Therapie und Surfactant-Applikation. Zahlreiche Studien zeigen, dass es durch die LISA<\/strong>-Methode zur Vermeidung von Komplikationen der maschinellen Beatmung kommen kann.8<\/a><\/sup><\/span><\/p>\n

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Die European Consensus Guidelines on the Management of RDS<\/em> best\u00e4tigt, dass Fr\u00fchgeborene nach M\u00f6glichkeit ohne mechanische Beatmung behandelt werden sollten. CPAP mit fr\u00fcher Surfactant-Applikation gilt als optimale Behandlungsform f\u00fcr S\u00e4uglinge mit Atemnotsyndrom. Die LISA<\/strong>-Methode ist die bevorzugte Methode der Surfactant-Applikation f\u00fcr spontanatmende Babys mit CPAP.9<\/a><\/sup><\/span><\/p>\n

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Klinischer Beweis<\/p>\n

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Ziel:<\/strong> \u0007In einer systematischen Analyse von sechs randomisiert kontrollierten Studien, mit 895 Fr\u00fchgeborenen, wurde die LISA-Methode mit intubierenden Beatmungsmethoden verglichen.<\/p>\n

Metaanalyse der klinischen Ergebnisse:<\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=“1_5,1_5,1_5,1_5,1_5″ _builder_version=“4.17.0″ _module_preset=“default“ custom_margin=“-10%||||false|false“ global_colors_info=“{}“][et_pb_column type=“1_5″ _builder_version=“4.17.0″ _module_preset=“default“ global_colors_info=“{}“][et_pb_counters _builder_version=“4.17.0″ _module_preset=“default“ custom_margin=“||||false|false“ global_colors_info=“{}“][et_pb_counter percent=“27″ bar_background_color=“#B3B3B3″ _builder_version=“4.17.0″ _module_preset=“default“ global_colors_info=“{}“ bar_background_color_default=“#2ea3f2″ use_percentages=“on“]Intubierte Beatmung[\/et_pb_counter][et_pb_counter percent=“20″ bar_background_color=“#d40075″ _builder_version=“4.17.0″ _module_preset=“default“ global_colors_info=“{}“ bar_background_color_default=“#2ea3f2″ use_percentages=“on“]LISA-Methode[\/et_pb_counter][\/et_pb_counters][et_pb_text _builder_version=“4.17.0″ _module_preset=“default“ text_font_size=“15px“ custom_margin=“-10%||||false|false“ global_colors_info=“{}“]<\/p>\n

Tod oder BPD36*<\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=“1_5″ _builder_version=“4.17.0″ _module_preset=“default“ global_colors_info=“{}“][et_pb_counters _builder_version=“4.17.0″ _module_preset=“default“ custom_margin=“0px||||false|false“ global_colors_info=“{}“][et_pb_counter percent=“10″ bar_background_color=“#B3B3B3″ _builder_version=“4.17.0″ _module_preset=“default“ global_colors_info=“{}“ bar_background_color_default=“#2ea3f2″ use_percentages=“on“]Intubierte Beatmung[\/et_pb_counter][et_pb_counter percent=“8″ bar_background_color=“#d40075″ _builder_version=“4.17.0″ _module_preset=“default“ global_colors_info=“{}“ bar_background_color_default=“#2ea3f2″ use_percentages=“on“]LISA-Methode[\/et_pb_counter][\/et_pb_counters][et_pb_text _builder_version=“4.17.0″ _module_preset=“default“ text_font_size=“15px“ custom_margin=“-10%||||false|false“ global_colors_info=“{}“]<\/p>\n

Tod <\/strong><\/p>\n

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BPD36* unter den \u00dcberlebenden <\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=“1_5″ _builder_version=“4.17.0″ _module_preset=“default“ global_colors_info=“{}“][et_pb_counters _builder_version=“4.17.0″ _module_preset=“default“ custom_margin=“0px||||false|false“ global_colors_info=“{}“][et_pb_counter percent=“27″ bar_background_color=“#B3B3B3″ _builder_version=“4.17.0″ _module_preset=“default“ global_colors_info=“{}“ bar_background_color_default=“#2ea3f2″ use_percentages=“on“]Intubierte Beatmung[\/et_pb_counter][et_pb_counter percent=“20″ bar_background_color=“#d40075″ _builder_version=“4.17.0″ _module_preset=“default“ global_colors_info=“{}“ bar_background_color_default=“#2ea3f2″ use_percentages=“on“]LISA-Methode[\/et_pb_counter][\/et_pb_counters][et_pb_text _builder_version=“4.17.0″ _module_preset=“default“ text_font_size=“15px“ custom_margin=“-10%||||false|false“ global_colors_info=“{}“]<\/p>\n

Notwendigkeit einer maschinellen Beatmung innerhalb 72h nach der Geburt<\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=“1_5″ _builder_version=“4.17.0″ _module_preset=“default“ global_colors_info=“{}“][et_pb_counters _builder_version=“4.17.0″ _module_preset=“default“ custom_margin=“0px||||false|false“ global_colors_info=“{}“][et_pb_counter percent=“74″ bar_background_color=“#B3B3B3″ _builder_version=“4.17.0″ _module_preset=“default“ global_colors_info=“{}“ bar_background_color_default=“#2ea3f2″ use_percentages=“on“]Intubierte Beatmung[\/et_pb_counter][et_pb_counter percent=“50″ bar_background_color=“#d40075″ _builder_version=“4.17.0″ _module_preset=“default“ global_colors_info=“{}“ bar_background_color_default=“#2ea3f2″ use_percentages=“on“]LISA-Methode[\/et_pb_counter][\/et_pb_counters][et_pb_text _builder_version=“4.17.0″ _module_preset=“default“ text_font_size=“15px“ custom_margin=“-10%||||false|false“ global_colors_info=“{}“]<\/p>\n

Notwendigkeit einer kontinuierlichen maschinellen Beatmung<\/strong><\/p>\n

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Ergebnisse: \u0007<\/strong>Mit der LISA-Methode ist die Notwendigkeit einer mechanischen Beatmung f\u00fcr S\u00e4uglinge mit ANS gesunken. Zus\u00e4tzlich gibt es u.a. eine signifikante Abnahme in der Kombination \u201eTod oder BPD36*\u201c.<\/p>\n

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UNSERE L\u00d6SUNG F\u00dcR DIE APPLIKATION VON SURFACTANT F\u00dcR FR\u00dcHGEBORENE MIT ATEMNOTSYNDROM<\/h3>\n
Eine Entwicklung in Zusammenarbeit mit Frau Priv.-Doz. Dr. Angela Kribs, Universit\u00e4tsklinikum K\u00f6ln (A\u00f6R)<\/h6>\n

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Die L\u00f6sung: surfcath\u2122<\/h2>\n

Applikationskatheter zur einfachen und pr\u00e4zisen Applikation von Surfactant f\u00fcr Fr\u00fchgeborene mit Atemnotsyndrom<\/p>\n

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Atraumatische Katheterspitze<\/p>\n

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